Invention Grant
- Patent Title: Peptides of CaV2.2 that inhibit pain
- Patent Title (中): 抑制疼痛的CaV2.2肽
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Application No.: US12190459Application Date: 2008-08-12
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Publication No.: US07829688B2Publication Date: 2010-11-09
- Inventor: Mary Garry , Ilya Bezprozvanny
- Applicant: Mary Garry , Ilya Bezprozvanny
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Fulbright & Jaworski, L.L.P.
- Main IPC: C07H21/00
- IPC: C07H21/00 ; C40B40/06
Abstract:
The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.
Public/Granted literature
- US20090068148A1 PEPTIDES OF CAV2.2 THAT INHIBIT PAIN Public/Granted day:2009-03-12
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