Invention Grant
US07829702B2 Racemic separation of 2,6-trans-dimethymorpholine 有权
外消旋分离2,6-反式二甲基吗啉

  • Patent Title: Racemic separation of 2,6-trans-dimethymorpholine
  • Patent Title (中): 外消旋分离2,6-反式二甲基吗啉
  • Application No.: US12159504
    Application Date: 2006-12-18
  • Publication No.: US07829702B2
    Publication Date: 2010-11-09
  • Inventor: Klaus DitrichFrank Haese
  • Applicant: Klaus DitrichFrank Haese
  • Applicant Address: DE Ludwigshafen
  • Assignee: BASF SE
  • Current Assignee: BASF SE
  • Current Assignee Address: DE Ludwigshafen
  • Agency: Connolly Bove Lodge & Hutz LLP
  • Priority: DE102005063192 20051230
  • International Application: PCT/EP2006/069862 WO 20061218
  • International Announcement: WO2007/077118 WO 20070712
  • Main IPC: C07D265/28
  • IPC: C07D265/28
Racemic separation of 2,6-trans-dimethymorpholine
Abstract:
A process for preparing optically active trans-2,6-dimethylmorpholine by (i) reacting racemic trans-2,6-dimethylmorpholine with D-mandelic acid, (ii) removing the salt formed from D-mandelic acid and one enantiomer of trans-2,6-dimethylmorpholine from the other enantiomer of trans-2,6-dimethylmorpholine and (iii) isolating the desired optically active trans-2,6-dimethylmorpholine.
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