Invention Grant
US07829731B2 Methylhydroxylaminopropanol derivative and its use as intermediate for preparation of 3-methylamino-1-(2-thienyl)propan-1-OL
有权
甲基羟基氨基丙醇衍生物及其作为制备3-甲基氨基-1-（2-噻吩基）丙-1-醇的中间体的用途
- Patent Title: Methylhydroxylaminopropanol derivative and its use as intermediate for preparation of 3-methylamino-1-(2-thienyl)propan-1-OL
- Patent Title (中): 甲基羟基氨基丙醇衍生物及其作为制备3-甲基氨基-1-（2-噻吩基）丙-1-醇的中间体的用途
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Application No.: US11926772Application Date: 2007-10-29
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Publication No.: US07829731B2Publication Date: 2010-11-09
- Inventor: Bo-Fong Chen , Jinun-Ban Yeh , Weichyun Wong
- Applicant: Bo-Fong Chen , Jinun-Ban Yeh , Weichyun Wong
- Applicant Address: TW Taoyuan
- Assignee: SCI Pharmtech, Inc.
- Current Assignee: SCI Pharmtech, Inc.
- Current Assignee Address: TW Taoyuan
- Agency: Sughrue Mion, PLLC
- Main IPC: C07D333/12
- IPC: C07D333/12
Abstract:
The present invention provides a methylhydroxylaminopropanol derivative and the methylhydroxylaminopropanol derivative of the present invention is used as an intermediate for preparation of 3-methylamino-1-(2-thienyl)propan-1-ol, which is an intermediate for preparation of (+)-(S)—N-methyl-3-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine oxalate. The present invention also provides a process for preparing 3-methylamino-1-(2-thienyl)propan-1-ol with higher yield and lower cost, wherein the methylhydroxylaminopropanol derivative is used as an intermediate.
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