A device for gripping a guide wire includes a body portion having an opening therethrough, and has an open position and a closed position. When the device is in the open position the guide wire may be passed through the opening. When the device is in the closed position the guide wire is gripped at more than one location thereby allowing force or torque to be applied to the guide wire. A device according to the invention may optionally, or instead, include (a) a snout to act as a guide wire director, (b) a structure, such as an opening, configured to receive an end of a guide wire package, (c) a structure for securing a body member to the device, and/or (d) a mechanism for advancing or retracting a guide wire. If the device includes one of these optional features, it need not be designed to grip a guide wire at two or more locations.