A color interpolation method and apparatus for interpolating missing color signals for each pixel of an image sensor. The color interpolation method includes forming a difference image channel by subtracting an R or B color value from a G color value in pixels adjacent to a pixel to be interpolated, detecting the direction of an edge to which the pixel to be interpolated belongs and selecting adjacent pixels to be used for color interpolation. By calculating a weight value indicating the direction of the edge and providing the weight value to the adjacent pixels to be used for color interpolation, and using the difference image values of the adjacent pixels and the weight values, a color component missing in the pixel to be interpolated can be calculated.