A method for evaluating an electrocardiogram is disclosed herein. The method includes measuring an electrical activity of a patient, processing the measured electrical activity to form a multi-lead signal, and extracting a segment of the multi-lead signal. The method for evaluating an electrocardiogram also includes transforming the segment of the multi-lead signal into a synthesized signal that is most representative of the patient's electrical activity, and evaluating the synthesized signal. A corresponding system for evaluating an electrocardiogram is also disclosed.