An aviation yoke HSI interface and flight deck control indicator and selector safety system enhances flight safety. The system incorporates a multi-controlled HSI with a yoke heading adjustment control, a yoke VOR radial selector, and a yoke heading centering control positioned on the captain yoke. The system may also incorporate a first officer multi-controlled HSI with a first officer yoke heading adjustment control, a first officer yoke VOR radial selector, and a first officer yoke heading and course centering control positioned on the first officer yoke. An autopilot mode indicator visually indicates whether an autopilot is flying according to a desired heading or according to a VOR radial signal. A side selector-indicator control permits selection of which side controls the flight of the aircraft. A first control unit and a second control unit may be in electrical communication with both sides to fly the aircraft in autopilot.