Invention Grant
- Patent Title: Heterocyclic sulfonamide inhibitors of beta amyloid production
- Patent Title (中): β-淀粉样蛋白生成的杂环磺酰胺抑制剂
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Application No.: US12576513Application Date: 2009-10-09
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Publication No.: US07842718B2Publication Date: 2010-11-30
- Inventor: Anthony Frank Kreft , Derek Cecil Cole , Kevin R. Woller , Joseph Raymond Stock , George Diamantidis , Dennis Michael Kubrak , Kristina Martha Kutterer , William J. Moore , David S. Casebier
- Applicant: Anthony Frank Kreft , Derek Cecil Cole , Kevin R. Woller , Joseph Raymond Stock , George Diamantidis , Dennis Michael Kubrak , Kristina Martha Kutterer , William J. Moore , David S. Casebier
- Applicant Address: US NJ Madison US MA Woburn
- Assignee: Wyeth LLC,ArQule, Inc.
- Current Assignee: Wyeth LLC,ArQule, Inc.
- Current Assignee Address: US NJ Madison US MA Woburn
- Agency: Howson & Howson LLP
- Agent Martha G. Munchhof
- Main IPC: A61K31/381
- IPC: A61K31/381 ; C07D333/34
Abstract:
Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, T, W, X, Y and Z are as defined herein are provided, together with pharmaceutically acceptable salt, hydrates and/or prodrugs thereof. Methods of using these compounds for inhibiting beta amyloid production and for treatment of Alzheimer's disease and Down's syndrome are described.
Public/Granted literature
- US20100022594A1 HETEROCYCLIC SULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION Public/Granted day:2010-01-28
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