Invention Grant
- Patent Title: Silk fibroin materials and use thereof
- Patent Title (中): 丝素蛋白材料及其用途
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Application No.: US10541182Application Date: 2004-01-07
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Publication No.: US07842780B2Publication Date: 2010-11-30
- Inventor: David L. Kaplan , Rina Nazarov , Gordana Vunjak-Novakovic , Lorenz Meinel
- Applicant: David L. Kaplan , Rina Nazarov , Gordana Vunjak-Novakovic , Lorenz Meinel
- Applicant Address: US MA Medford US MA Cambridge
- Assignee: Trustees of Tufts College,Massachusetts Institute of Technology
- Current Assignee: Trustees of Tufts College,Massachusetts Institute of Technology
- Current Assignee Address: US MA Medford US MA Cambridge
- Agency: Nixon Peabody LLP
- International Application: PCT/US2004/000255 WO 20040107
- International Announcement: WO2004/062697 WO 20040729
- Main IPC: A23J7/00
- IPC: A23J7/00 ; A61K38/08 ; A61K38/39 ; C07K7/06 ; C07K7/08
Abstract:
The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin scaffolds described herein can be adjusted as to mimic the gradient of densities found in natural tissue. Accordingly, methods for engineering of 3-dimensional tissue, e.g. bone and cartilage, using the silk fibroin scaffold material are also provided.
Public/Granted literature
- US20060273279A1 Electrospun pharmaceutical compositions Public/Granted day:2006-12-07
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