Invention Grant
- Patent Title: Human CDR-grafted antibody and antibody fragment thereof
- Patent Title (中): 人CDR移植的抗体及其抗体片段
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Application No.: US12395214Application Date: 2009-02-27
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Publication No.: US07842797B2Publication Date: 2010-11-30
- Inventor: Kenya Shitara , Kazuyasu Nakamura , Emi Hosaka , Akiko Shimizu , Masamichi Koike
- Applicant: Kenya Shitara , Kazuyasu Nakamura , Emi Hosaka , Akiko Shimizu , Masamichi Koike
- Applicant Address: JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee: Kyowa Hakko Kirin Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2001-265144 20010831
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/00 ; C07K16/28
Abstract:
A human CDR-grafted antibody or the antibody fragment thereof which specifically reacts with the extracellular region of human CC chemokine receptor 4 (CCR4) but does not react with a human blood platelet; a human CDR-grafted antibody or the antibody fragment thereof which specifically reacts with the extracellular region of CCR4 and has a cytotoxic activity against a CCR4-expressing cell; and a medicament, a therapeutic agent or a diagnostic agent comprising at least one of the antibodies and the antibody fragments thereof as an active ingredient.
Public/Granted literature
- US20090227012A1 Human CDR-Grafted Antibody and Antibody Fragment Thereof Public/Granted day:2009-09-10
Information query
