Invention Grant
- Patent Title: Histone deacetylase inhibitors and methods of use thereof
- Patent Title (中): 组蛋白脱乙酰酶抑制剂及其使用方法
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Application No.: US10614498Application Date: 2003-07-07
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Publication No.: US07842835B2Publication Date: 2010-11-30
- Inventor: Alan P. Kozikowski , Anatoly Dritschilo , Mira Jung , Pavel A. Petukhov , Bin Chen
- Applicant: Alan P. Kozikowski , Anatoly Dritschilo , Mira Jung , Pavel A. Petukhov , Bin Chen
- Applicant Address: US DC Washington
- Assignee: Georgetown University
- Current Assignee: Georgetown University
- Current Assignee Address: US DC Washington
- Agency: Foley Hoag, LLP
- Main IPC: C07C275/04
- IPC: C07C275/04 ; A61K31/17
Abstract:
The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention.
Public/Granted literature
- US20050014839A1 Histone deacetylase inhibitors and methods of use thereof Public/Granted day:2005-01-20
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