The present invention provides a system and method that mitigates audio interference before and/or during an audio session, and in particular, when a high quality audio session is desired. The system includes an audio component that determines whether an audio session is to commence and a control component that interfaces with the audio component and reduces activity associated with a subset of a plurality of computer components that may interfere with the audio session. The system may also include at least one power management system to facilitate reducing power consumption and activity of the computer component(s). The method involves determining that an audio session is desired and switching one or more computer components to a minimal interference mode prior to commencing the audio session. The method may also involve calling at least on API to facilitate the switching of the computer component(s).