Optical signals are passed in an optical medium using an approach that facilitates the mitigation of interference. According to an example embodiment, a filtering-type approach is used with an optical signal conveyed in an optical fiber, such as a multimode fiber (MMF) or a multimode waveguide. Adaptive spatial domain signal processing, responsive to a feedback signal indicative of data conveyed in the multimode waveguide, is used to mitigate interference in optical signals conveyed in the multimode waveguide.