Methods and apparatus for spatial sound generation for screen navigation are disclosed. An example method for spatial sound generation comprises receiving an indication of a cursor focus position, where the cursor focus position corresponds with a location on a display device. The example method further includes receiving speech information associated with an object situated at the location on the display device. The example method also includes modifying the speech information based on the indication of the cursor focus position such that the modified speech information spatially represents the location on the display device.