The invention provides a high-pressure hydrogen production apparatus for preventing hydrogen gas from leaking toward an anode side and for obtaining excellent electrolytic efficiency. The apparatus includes a single cell having a solid polymer electrolyte membrane, power feeders, separators, and fluid channels provided in respective separators. High-pressure hydrogen gas accompanied by water is obtained in the fluid channel by supplying water to the fluid channel and applying current to each power feeder to electrolyze water. The obtained hydrogen gas and water are subjected to gas-liquid separation in a second compartment of a high-pressure vessel, and hydrogen gas thus separated is used to press a barrier member towards the single cell. The separated water is supplied to the fluid channel through the hydrogen gas guide channel.