Invention Grant
- Patent Title: Method for producing solid galenic formulations using a crosslinked non-thermoplastic carrier
- Patent Title (中): 使用交联的非热塑性载体制备固体盖仑制剂的方法
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Application No.: US10530483Application Date: 2003-10-09
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Publication No.: US07846477B2Publication Date: 2010-12-07
- Inventor: Jörg Rosenberg , Gunther Berndl , Markus Magerlein
- Applicant: Jörg Rosenberg , Gunther Berndl , Markus Magerlein
- Applicant Address: DE Wiesbaden
- Assignee: Abbott GmbH & Co. KG
- Current Assignee: Abbott GmbH & Co. KG
- Current Assignee Address: DE Wiesbaden
- Agency: Novak Druce + Quigg LLP
- Priority: DE10247037 20021009
- International Application: PCT/EP03/11205 WO 20031009
- International Announcement: WO2004/032903 WO 20040422
- Main IPC: A61K9/20
- IPC: A61K9/20 ; B27N3/00

Abstract:
The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic polymers, lipids, sugar alcohols and solubilizing agents, c) 0.1 to 49.5 wt. % of at least one active principle, at a temperature not less than the softening temperature of the adjuvant but rising to at least 70° C.; then in cooling the resulting paste. Said solid galenic formulations quickly disintegrate in an aqueous medium.
Public/Granted literature
- US20060257470A1 Method for producing solid galenic formulations using a crosslinked non-thermoplastic carrier Public/Granted day:2006-11-16
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