Invention Grant
US07846657B2 Detection of target nucleotide sequences using ligation assays with improved oligonucleotide probe pairs
有权
使用具有改进的寡核苷酸探针对的连接测定法检测靶核苷酸序列
- Patent Title: Detection of target nucleotide sequences using ligation assays with improved oligonucleotide probe pairs
- Patent Title (中): 使用具有改进的寡核苷酸探针对的连接测定法检测靶核苷酸序列
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Application No.: US10560968Application Date: 2004-06-16
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Publication No.: US07846657B2Publication Date: 2010-12-07
- Inventor: Michael Josephus Theresia Van Eijk
- Applicant: Michael Josephus Theresia Van Eijk
- Applicant Address: NL Wageningen
- Assignee: Keygene N.V.
- Current Assignee: Keygene N.V.
- Current Assignee Address: NL Wageningen
- Agency: Browdy and Neimark, PLLC
- Priority: WOPCT/NL03/00444 20040723
- International Application: PCT/NL2004/000428 WO 20040616
- International Announcement: WO2004/111271 WO 20041223
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/04
Abstract:
A pair of oligonucleotide probes comprising a first oligonucleotide probe that comprises a first clamp section that is capable of hybridising to a second clamp section of a second oligonucleotide probe and a first target section that is capable of hybridising to a first section of a target DNA sequence to be detected, a second oligonucleotide probe that comprises a second clamp section that is capable of hybridising to the first clamp section of the first oligonucleotide probe and a second target section that is capable of hybridising to a second section of the target DNA sequence to be detected.
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