Invention Grant
US07846683B2 Method for identifying agents which modulate cell growth or survival
有权
用于鉴定调节细胞生长或存活的药剂的方法
- Patent Title: Method for identifying agents which modulate cell growth or survival
- Patent Title (中): 用于鉴定调节细胞生长或存活的药剂的方法
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Application No.: US11575887Application Date: 2005-09-23
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Publication No.: US07846683B2Publication Date: 2010-12-07
- Inventor: Stephen F. Vatner , Christopher Depre
- Applicant: Stephen F. Vatner , Christopher Depre
- Applicant Address: US NJ New Brunswick
- Assignee: University of Medicine and Dentistry of New Jersey
- Current Assignee: University of Medicine and Dentistry of New Jersey
- Current Assignee Address: US NJ New Brunswick
- International Application: PCT/US2005/034228 WO 20050923
- International Announcement: WO2006/036822 WO 20060406
- Main IPC: C12Q1/48
- IPC: C12Q1/48
Abstract:
The present invention relates to a method for identifying an agent. for modulating cell growth or survival. The method involves the identification of an agent which modulates the net ratio of nuclear-localized versus cytosolic-localized H11 kinase or mutant H11 kinase in a cell. A method for diagnosing a cancer associated with H11 kinase or Akt activation in a subject is also provided.
Public/Granted literature
- US20080096237A1 Method for Identifying Agents Which Modulate Cell Growth or Survival Public/Granted day:2008-04-24
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