Invention Grant
- Patent Title: Flap endonuclease mutants
- Patent Title (中): 瓣内切核酸突变体
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Application No.: US11658096Application Date: 2005-01-21
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Publication No.: US07846704B2Publication Date: 2010-12-07
- Inventor: Eriko Matsui , Ikuo Matsui
- Applicant: Eriko Matsui , Ikuo Matsui
- Applicant Address: JP Tokyo
- Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2004-216527 20040723
- International Application: PCT/JP2005/000792 WO 20050121
- International Announcement: WO2006/011253 WO 20060202
- Main IPC: C12N9/16
- IPC: C12N9/16 ; C07K14/00 ; C12N15/00 ; C12P21/00 ; C12Q1/44 ; C12N1/21 ; C12N5/10 ; C07H21/00
Abstract:
A mutation is introduced into the substrate-binding site of flap endonuclease to prepare a mutant with modified substrate specificity. Using the mutant as a reagent for the analysis of genetic polymorphism, the analysis of genetic polymorphism can be performed more accurately, easily and sensitively as compared with conventional methods.
Public/Granted literature
- US20080118922A1 Flap Endonuclease Mutants Public/Granted day:2008-05-22
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