Invention Grant
- Patent Title: Study of polymer molecules and conformations with a nanopore
- Patent Title (中): 研究聚合物分子和与纳米孔的构象
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Application No.: US10918959Application Date: 2004-08-16
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Publication No.: US07846738B2Publication Date: 2010-12-07
- Inventor: Jene A. Golovchenko , Jiali Li , Derek Stein , Marc H. Gershow
- Applicant: Jene A. Golovchenko , Jiali Li , Derek Stein , Marc H. Gershow
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Clark & Elbing LLP
- Agent Kristina Bieker-Brady
- Main IPC: G01N33/00
- IPC: G01N33/00
Abstract:
The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.
Public/Granted literature
- US20060003458A1 Study of polymer molecules and conformations with a nanopore Public/Granted day:2006-01-05
Information query
