Invention Grant
US07846746B2 Methods of analysis and labeling of protein-protein interactions
有权
蛋白质 - 蛋白质相互作用的分析和标记方法
- Patent Title: Methods of analysis and labeling of protein-protein interactions
- Patent Title (中): 蛋白质 - 蛋白质相互作用的分析和标记方法
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Application No.: US10474465Application Date: 2002-04-10
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Publication No.: US07846746B2Publication Date: 2010-12-07
- Inventor: Peter Nollau , Bruce J. Mayer
- Applicant: Peter Nollau , Bruce J. Mayer
- Applicant Address: US MA Boston
- Assignee: Children's Medical Center Corporation
- Current Assignee: Children's Medical Center Corporation
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- International Application: PCT/US02/11272 WO 20020410
- International Announcement: WO02/083846 WO 20021024
- Main IPC: G01N33/543
- IPC: G01N33/543
Abstract:
We have discovered a new method to analyze and characterize complex cell signaling networks. The method is based on specific binding of protein-protein interaction modules to a single type of protein or a mixture of proteins. The method utilizes a number of different protein-protein interaction domains as probes or sensors for the signaling state of the system under investigation.
Public/Granted literature
- US20040157279A1 Methods of analysis and labeling of protein-protein interactions Public/Granted day:2004-08-12
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