Invention Grant
- Patent Title: RNAi modulation of TGF-beta and therapeutic uses thereof
- Patent Title (中): TGF-β的RNAi调节及其治疗用途
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Application No.: US11724790Application Date: 2007-03-15
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Publication No.: US07846908B2Publication Date: 2010-12-07
- Inventor: Hans-Peter Vornlocher , Pamela Tan , Rainer Constien
- Applicant: Hans-Peter Vornlocher , Pamela Tan , Rainer Constien
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70 ; C07H21/04
Abstract:
The present invention concerns methods of treatment using transforming growth factor beta (TGF-beta) modulators. More specifically, the invention concerns methods of treating disorders associated with undesirable TGF-beta signaling, by administering short interfering RNA which down-regulate the expression of TGF-beta, and agents useful therein.
Public/Granted literature
- US20080015161A1 RNAi modulation of TGF-beta and therapeutic uses thereof Public/Granted day:2008-01-17
Information query
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