Invention Grant
- Patent Title: 4-imidazolin-2-one compounds
- Patent Title (中): 4-咪唑啉-2-酮化合物
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Application No.: US12270826Application Date: 2008-11-13
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Publication No.: US07846933B2Publication Date: 2010-12-07
- Inventor: Akira Kubo , Ritsuo Imashiro , Hiroaki Sakurai , Hidetaka Miyoshi , Akihito Ogasawara , Hajime Hiramatsu , Tatsuo Nakajima , Tetsu Nakane
- Applicant: Akira Kubo , Ritsuo Imashiro , Hiroaki Sakurai , Hidetaka Miyoshi , Akihito Ogasawara , Hajime Hiramatsu , Tatsuo Nakajima , Tetsu Nakane
- Applicant Address: JP Osaka-shi
- Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee Address: JP Osaka-shi
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2001-324029 20011022; JP2002-263680 20020910; JP2003-116076 20030421
- Main IPC: C07D403/04
- IPC: C07D403/04 ; A61K31/4439

Abstract:
The present invention relates to a compound of the formula [I]: wherein G1 is an alkyl which is substituted by a halogen atom or an alkoxy, or a group of the formula: wherein ring B is benzene ring which may be substituted, etc., Q1 and Q2 may be the same or different, and each is hydrogen atom, a halogen atom or an alkyl, n is 0, 1, 2, 3 or 4, R1 is hydrogen atom, an alkyl which may be substituted, a cycloalkyl which may be substituted, a phenyl which may be substituted, etc., Z1, Z2, Z3 and Z4 may be the same or different, and each is CH or N, provided that 3 or more of Z1, Z2, Z3 and Z4 should not be N at the same time, G2 is hydrogen atom, —NR3R4, —OR5, etc., where R3 to R8 each is independently hydrogen atom, an alkyl which may be substituted, an alkenyl, an alkynyl, etc., or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20090088422A1 4-IMIDAZOLIN-2-ONE COMPOUNDS Public/Granted day:2009-04-02
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