Invention Grant
US07846936B2 Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
有权
用于治疗涉及细胞增殖，骨髓瘤细胞迁移或凋亡或血管发生的疾病的组合
- Patent Title: Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
- Patent Title (中): 用于治疗涉及细胞增殖，骨髓瘤细胞迁移或凋亡或血管发生的疾病的组合
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Application No.: US12140661Application Date: 2008-06-17
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Publication No.: US07846936B2Publication Date: 2010-12-07
- Inventor: Frank Hilberg , Flavio Solca , Anke Baum , Jacobus C. A. van Meel
- Applicant: Frank Hilberg , Flavio Solca , Anke Baum , Jacobus C. A. van Meel
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Anthony P. Bottino
- Priority: EP03009587 20030429; EP04000508 20040113; EP04001171 20040121
- Main IPC: A61K31/497
- IPC: A61K31/497
Abstract:
The present invention relates to a pharmaceutical combination for the treatment of diseases which involves cell proliferation, migration or apoptosis of myeloma cells, or angiogenesis. The invention also relates to a method for the treatment of said diseases, comprising co-administration of effective amounts of specific active compounds and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of these specific compounds and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations.
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