Invention Grant
- Patent Title: Chroman derivatives as estrogenic compounds
- Patent Title (中): 色甘酸衍生物作为雌激素化合物
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Application No.: US12437883Application Date: 2009-05-08
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Publication No.: US07846966B2Publication Date: 2010-12-07
- Inventor: Gerrit Herman Veeneman , Neeltje Miranda Teerhuis
- Applicant: Gerrit Herman Veeneman , Neeltje Miranda Teerhuis
- Applicant Address: NL Oss
- Assignee: N.V. Organon
- Current Assignee: N.V. Organon
- Current Assignee Address: NL Oss
- Agent Maria V. Marucci; Valerie J. Camara
- Priority: EP00200713 20000301
- Main IPC: A01N43/16
- IPC: A01N43/16 ; C07D311/00
Abstract:
The invention provides chroman compounds having formula 1 wherein R1 is (1C-4C)alkyl, (2C-4C)alkenyl or (2C-4C)alkynyl, and independently R1 has a cis-orientation in relation to the exocyclic phenyl group at the 2-position of the skeleton; R4 is H, Hal, CF3, OH or (1C-2C)alkyloxy; R2, R3, and R5 are independently H, Hal, CF3, (1C-4C)alkyl, (2C-4C)alkenyl or (2C-4C)alkynyl and prodrugs thereof for the manufacture of a medicine for estrogen-receptor related treatments.
Public/Granted literature
- US20090221695A1 Chroman Derivatives as Estrogenic Compounds Public/Granted day:2009-09-03
Information query
IPC分类:
