Invention Grant
US07847062B2 Pharmacokinetic modulation and compositions for modified FN3 polypeptides
有权
药代动力学调节和修饰的FN3多肽的组合物
- Patent Title: Pharmacokinetic modulation and compositions for modified FN3 polypeptides
- Patent Title (中): 药代动力学调节和修饰的FN3多肽的组合物
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Application No.: US11482641Application Date: 2006-07-07
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Publication No.: US07847062B2Publication Date: 2010-12-07
- Inventor: Yan Chen , Elena Getmanova , Martin C. Wright , Alan S. Harris , Ai Ching Lim , Jochem Gokemeijer , Lin Sun , Michael Wittekind
- Applicant: Yan Chen , Elena Getmanova , Martin C. Wright , Alan S. Harris , Ai Ching Lim , Jochem Gokemeijer , Lin Sun , Michael Wittekind
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: Ropes & Gray LLP
- Main IPC: C07K14/78
- IPC: C07K14/78 ; A61K38/39
Abstract:
The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
Public/Granted literature
- US20070160533A1 Pharmacokinetic modulation and compositions for modified Fn3 polypeptides Public/Granted day:2007-07-12
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