Invention Grant
- Patent Title: RNA interference induction element and use thereof
- Patent Title (中): RNA干扰诱导元件及其用途
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Application No.: US11920508Application Date: 2006-05-15
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Publication No.: US07847089B2Publication Date: 2010-12-07
- Inventor: Kojiro Ishii , Kohta Takahashi
- Applicant: Kojiro Ishii , Kohta Takahashi
- Applicant Address: JP Fukuoka JP Saitama
- Assignee: Kurume University,Japan Science and Technology Agency
- Current Assignee: Kurume University,Japan Science and Technology Agency
- Current Assignee Address: JP Fukuoka JP Saitama
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2005-145876 20050518
- International Application: PCT/JP2006/310079 WO 20060515
- International Announcement: WO2006/123800 WO 20061123
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A01N43/04 ; A61K31/70
Abstract:
The present invention provides an RNA interference induction element containing a nucleotide sequence selected from among the nucleotide sequences (a) to (c) below: (a) a nucleotide sequence containing SEQ ID NO:1 or a sequence complementary thereto; (b) a nucleotide sequence containing at least 15 continuous nucleotides present in the nucleotide sequence (a) above, and possessing RNA interference induction potential; (c) a nucleotide sequence having a homology of at least 70% to any one of the nucleotide sequences (a) and (b) above, and possessing RNA interference induction potential. Using the RNA interference induction element of the present invention, it is easily possible to knock down a desired target gene, and to produce a siRNA for a desired target gene.
Public/Granted literature
- US20090215644A1 Rna interference induction element and use thereof Public/Granted day:2009-08-27
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