Invention Grant
US07854918B2 Composition for medical use having improved water-solubility of peptide and metal-labeling efficiency and preparation for medical use comprising metal-labeled peptide
有权
具有改进的肽的水溶性和金属标记效率的用于医疗用途的组合物和包含金属标记的肽的用于医疗用途的制剂
- Patent Title: Composition for medical use having improved water-solubility of peptide and metal-labeling efficiency and preparation for medical use comprising metal-labeled peptide
- Patent Title (中): 具有改进的肽的水溶性和金属标记效率的用于医疗用途的组合物和包含金属标记的肽的用于医疗用途的制剂
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Application No.: US10591252Application Date: 2005-03-23
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Publication No.: US07854918B2Publication Date: 2010-12-21
- Inventor: Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
- Applicant: Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
- Applicant Address: JP Tokyo
- Assignee: Nihon Medi-Physics Co., Ltd.
- Current Assignee: Nihon Medi-Physics Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2004-089620 20040325
- International Application: PCT/JP2005/005182 WO 20050323
- International Announcement: WO2005/092396 WO 20051006
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14
Abstract:
By preliminarily dissolving a basic organic compound in an aqueous solvent in which a peptide usable in metal-labeling is to be dissolved, the solubility of the peptide is improved and thus metal-labeling can be carried out without heating. A composition for medical use containing a peptide usable in metal-labeling and a basic organic compound acceptable as a pharmaceutical additive can be utilized as a preparation useful in image diagnosis, radiotherapy and so on.
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