Invention Grant
US07855214B2 Fused cyclic systems useful as inhibitors of TEC family protein kinases
有权
融合的循环系统可用作TEC家族蛋白激酶的抑制剂
- Patent Title: Fused cyclic systems useful as inhibitors of TEC family protein kinases
- Patent Title (中): 融合的循环系统可用作TEC家族蛋白激酶的抑制剂
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Application No.: US11046664Application Date: 2005-01-26
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Publication No.: US07855214B2Publication Date: 2010-12-21
- Inventor: Juan-Miguel Jimenez , Sanjay Patel , David Kay , Ronald Knegtel , Oliver Philps
- Applicant: Juan-Miguel Jimenez , Sanjay Patel , David Kay , Ronald Knegtel , Oliver Philps
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Jennifer G. Che
- Main IPC: C07D487/22
- IPC: C07D487/22 ; C07D487/14 ; A61K31/519 ; A61P35/00 ; A61P29/00
Abstract:
The present invention relates to compounds useful as inhibitors of Tec family protein kinases. These compounds have the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, G, Cy1, and X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
Public/Granted literature
- US20050209255A1 Compositions useful as inhibitors of protein kinases Public/Granted day:2005-09-22
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