Invention Grant
US07855224B2 Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
有权
吲哚衍生物作为用于治疗认知和睡眠障碍，肥胖症和其他CNS疾病的组胺3受体抑制剂
- Patent Title: Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
- Patent Title (中): 吲哚衍生物作为用于治疗认知和睡眠障碍，肥胖症和其他CNS疾病的组胺3受体抑制剂
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Application No.: US12284574Application Date: 2008-09-23
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Publication No.: US07855224B2Publication Date: 2010-12-21
- Inventor: Youssef L. Bennani , Michael G. Campbell , David Dastrup , Emilie Porter Huck
- Applicant: Youssef L. Bennani , Michael G. Campbell , David Dastrup , Emilie Porter Huck
- Applicant Address: US OH Cleveland
- Assignee: Athersys, Inc.
- Current Assignee: Athersys, Inc.
- Current Assignee Address: US OH Cleveland
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- Main IPC: A61K31/404
- IPC: A61K31/404
Abstract:
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.
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