The replaceable elastic hand grip for framed mobility devices such as walkers that have a substantially elliptical gripping portion with at least one hole, the replaceable hand grip includes a substantially elliptical hand grip cover which includes an opening to form a C-shape cross section for securely installing the grip over the gripping portion of the frame of the mobility device. The hand grip further includes a mechanical means, such as a normally mounted pin on the inner surface of the grip cover that mates with the hole of the gripping portion of the mobility device so that the hand grip is prevented from slipping. The elastic and non-absorbent hand grip provides a replaceable, sanitary, stable grasping point for the user of the framed mobility device.