A screw, in particular a self-tapping screw, has a screw thread which covers up to the front end of the screw formed as a drilling tip or cutting tip. In the front area, starting with a distance from the front end of the screw, there is an opposite thread showing the same pitch as the screw thread, however, its thread height is lower than the thread height of the screw thread. This second, opposite single-thread, double-thread or triple-thread/multi-thread forms a cutting edge with its thread edge which is used to cut fibers in order to reduce wedge effect during screwing in the screw. The screw is particularly suitable for wood or wood-like materials in the edge areas of structural elements.