Invention Grant
- Patent Title: Protease inhibition for prevention or treatment of heart failure
- Patent Title (中): 用于预防或治疗心力衰竭的蛋白酶抑制
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Application No.: US11066839Application Date: 2005-02-25
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Publication No.: US07862811B2Publication Date: 2011-01-04
- Inventor: Clifford Greyson , Gregory Schwartz
- Applicant: Clifford Greyson , Gregory Schwartz
- Applicant Address: US CO Boulder
- Assignee: Regents of the University of Colorado
- Current Assignee: Regents of the University of Colorado
- Current Assignee Address: US CO Boulder
- Agency: Fulbright & Jaworski
- Main IPC: A61K38/43
- IPC: A61K38/43
Abstract:
Methods, and compositions to prevent and/or treat acute or chronic right ventricular failure from pressure over load (RVPO). In one embodiment, the method includes the inhibition of at least one cysteine protease. In other embodiments, the method includes the inhibition of MMP activity to prevent or treat right ventricular failure from acute pressure over load (RVPO). In another embodiment, combination therapies are included to inhibit cysteine protease activity and MMP activity.
Public/Granted literature
- US20050238633A1 Protease inhibition for prevention or treatment of heart failure Public/Granted day:2005-10-27
Information query
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