Invention Grant
- Patent Title: Immunoglobulin chimeric monomer-dimer hybrids
- Patent Title (中): 免疫球蛋白嵌合单体 - 二聚体杂交体
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Application No.: US11588431Application Date: 2006-10-27
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Publication No.: US07862820B2Publication Date: 2011-01-04
- Inventor: Robert T. Peters , Adam R. Mezo , Daniel S. Rivera , Alan J. Bitonti , Susan C. Low
- Applicant: Robert T. Peters , Adam R. Mezo , Daniel S. Rivera , Alan J. Bitonti , Susan C. Low
- Applicant Address: US MA Waltham
- Assignee: Syntonix Pharmaceuticals, Inc.
- Current Assignee: Syntonix Pharmaceuticals, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K16/00 ; C12P21/08
Abstract:
The invention relates to a chimeric monomer-dimer hybrid protein that comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first polypeptide chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
Public/Granted literature
- US20070172928A1 Immunoglobulin chimeric monomer-dimer hybrids Public/Granted day:2007-07-26
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