Invention Grant
- Patent Title: Modulation of C-reactive protein expression
- Patent Title (中): C反应蛋白表达调控
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Application No.: US11969208Application Date: 2008-01-03
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Publication No.: US07863252B2Publication Date: 2011-01-04
- Inventor: Rosanne M. Crooke , Mark J. Graham
- Applicant: Rosanne M. Crooke , Mark J. Graham
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc. Patent Dept. Jones Day
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12Q1/68 ; C12N5/00

Abstract:
Compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise oligonucleotides, targeted to nucleic acid encoding C-reactive protein. Methods of using these compounds for modulation of C-reactive protein expression and for diagnosis and treatment of disease associated with expression of C-reactive protein are provided.
Public/Granted literature
- US20090170799A1 MODULATION OF C-REACTIVE PROTEIN EXPRESSION Public/Granted day:2009-07-02
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