Invention Grant
US07863265B2 2-azetidinone derivatives and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia
失效
2-氮杂环丁酮衍生物及其作为治疗高脂血症的胆固醇吸收抑制剂的用途
- Patent Title: 2-azetidinone derivatives and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia
- Patent Title (中): 2-氮杂环丁酮衍生物及其作为治疗高脂血症的胆固醇吸收抑制剂的用途
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Application No.: US11993033Application Date: 2006-06-19
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Publication No.: US07863265B2Publication Date: 2011-01-04
- Inventor: Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
- Applicant: Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: Pepper Hamilton LLP
- Priority: SE0501425 20050620
- International Application: PCT/SE2006/000741 WO 20060619
- International Announcement: WO2006/137782 WO 20061228
- Main IPC: A61K31/397
- IPC: A61K31/397 ; C07D205/08 ; C07D413/12 ; C07D319/06 ; A61P3/06

Abstract:
Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
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