Invention Grant
- Patent Title: Isethionate salt of a selective CDK4 inhibitor
- Patent Title (中): 选择性CDK4抑制剂的羟乙基磺酸盐
-
Application No.: US11861958Application Date: 2007-09-26
-
Publication No.: US07863278B2Publication Date: 2011-01-04
- Inventor: Vladimir Genukh Beylin , Anthony Clyde Blackburn , David Thomas Erdman , Peter Laurence Toogood
- Applicant: Vladimir Genukh Beylin , Anthony Clyde Blackburn , David Thomas Erdman , Peter Laurence Toogood
- Applicant Address: US NJ Morris Plains
- Assignee: Warner-Lambert CompanyLLC
- Current Assignee: Warner-Lambert CompanyLLC
- Current Assignee Address: US NJ Morris Plains
- Agent Keith D. Hutchinson; Jeffrey H. Tidwell
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/497 ; A61P35/00 ; A61P29/00
Abstract:
Disclosed are polymorphs of the isethionate salt of 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, which is a selective cyclin-dependent kinase 4 (CDK4) inhibitor useful for treating inflammation and cell proliferative diseases such as cancer and restenosis.
Public/Granted literature
- US20080021037A1 ISETHIONATE SALT OF A SELECTIVE CDK4 INHIBITOR Public/Granted day:2008-01-24
Information query
