Invention Grant
US07863291B2 Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands
有权
奎宁环化合物作为α-7烟碱乙酰胆碱受体配体
- Patent Title: Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands
- Patent Title (中): 奎宁环化合物作为α-7烟碱乙酰胆碱受体配体
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Application No.: US12423299Application Date: 2009-04-14
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Publication No.: US07863291B2Publication Date: 2011-01-04
- Inventor: James H. Cook, II , Ivar M. McDonald , Dalton King , Richard E. Olson , Nenghui Wang , Christiana I. Iwuagwu , F. Christopher Zusi , John E. Macor
- Applicant: James H. Cook, II , Ivar M. McDonald , Dalton King , Richard E. Olson , Nenghui Wang , Christiana I. Iwuagwu , F. Christopher Zusi , John E. Macor
- Applicant Address: US NJ Frinceton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Frinceton
- Agent James Epperson; Aldo A. Algieri
- Main IPC: A01N43/90
- IPC: A01N43/90
Abstract:
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.
Public/Granted literature
- US20090270405A1 QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS Public/Granted day:2009-10-29
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