Invention Grant
- Patent Title: Bridged ring structures as pharmaceutical agents
- Patent Title (中): 桥接环结构作为药剂
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Application No.: US10576228Application Date: 2004-10-13
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Publication No.: US07863298B2Publication Date: 2011-01-04
- Inventor: Brenton T. Flatt , Richard Martin , Raju Mohan , Brett Murphy
- Applicant: Brenton T. Flatt , Richard Martin , Raju Mohan , Brett Murphy
- Applicant Address: US CA South San Francisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/US2004/033666 WO 20041013
- International Announcement: WO2005/037755 WO 20050428
- Main IPC: A61K31/451
- IPC: A61K31/451 ; C07D211/14

Abstract:
The present invention is directed to 1α,25-dihydroxyvitamin D3 mimics which modulate the vitamin D receptor (VDR). The invention is further directed to pharmaceutical compositions and methods for the treatment, prevention or amelioration of one or more symptoms of disease or disorder related to the activity of the vitamin D receptor using an effective amount of a compound of formula (I).
Public/Granted literature
- US20070225377A1 Bridged Ring Structures as Pharmaceutical Agents Public/Granted day:2007-09-27
Information query
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