Invention Grant
US07863413B2 Peptide protein translation inhibitor and the use thereof for protein translation control
有权
肽蛋白翻译抑制剂及其在蛋白质翻译控制中的应用
- Patent Title: Peptide protein translation inhibitor and the use thereof for protein translation control
- Patent Title (中): 肽蛋白翻译抑制剂及其在蛋白质翻译控制中的应用
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Application No.: US10565438Application Date: 2004-07-20
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Publication No.: US07863413B2Publication Date: 2011-01-04
- Inventor: Bertrand Cosson , Luc Paillard , Vincent Legagneux , Howard Osborne
- Applicant: Bertrand Cosson , Luc Paillard , Vincent Legagneux , Howard Osborne
- Applicant Address: FR Paris FR Rennes
- Assignee: Centre National de la Recherche Scientifique (CNRS),Universite de Rennes 1
- Current Assignee: Centre National de la Recherche Scientifique (CNRS),Universite de Rennes 1
- Current Assignee Address: FR Paris FR Rennes
- Agency: Young & Thompson
- Priority: FR0350357 20030721
- International Application: PCT/FR2004/050345 WO 20040720
- International Announcement: WO2005/010038 WO 20050203
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K51/00
Abstract:
A peptide protein translation inhibitor has a size greater than 250 amino acids and it includes an amino acid sequence which is at least for 85% identical to an amino acid sequence SEQ ID No 1. It also relates to a fusion polypeptide which specifically inhibits an interesting target polynucleotide translation, in which the polypeptide includes the above defined inhibiting peptide fused with a RNA binding protein.
Public/Granted literature
- US20070105764A1 Peptide protein translation inhibitor and the use thereof for protein translation control Public/Granted day:2007-05-10
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