Invention Grant
US07863451B2 Processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines
有权
制备取代的2-（2,6-二氧代哌啶-3-基）-1-氧代异吲哚啉的方法
- Patent Title: Processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines
- Patent Title (中): 制备取代的2-（2,6-二氧代哌啶-3-基）-1-氧代异吲哚啉的方法
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Application No.: US11219589Application Date: 2005-09-01
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Publication No.: US07863451B2Publication Date: 2011-01-04
- Inventor: George W. Muller , Roger Chen , Manohar Tukaram Saindane , Chuansheng Ge
- Applicant: George W. Muller , Roger Chen , Manohar Tukaram Saindane , Chuansheng Ge
- Applicant Address: US NJ Summit
- Assignee: Celgene Corporation
- Current Assignee: Celgene Corporation
- Current Assignee Address: US NJ Summit
- Agency: Jones Day
- Main IPC: C07D403/04
- IPC: C07D403/04
Abstract:
The present invention concerns new processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines which are useful for preventing or treating diseases or conditions related to an abnormally high level or activity of TNFα. The invention provides processes for the commercial production of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines including, but not limited to, the therapeutically active 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione.
Public/Granted literature
- US20060052609A1 Processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines Public/Granted day:2006-03-09
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