Invention Grant
US07863464B2 Triptolide lactone ring derivatives as immunomodulators and anticancer agents
有权
雷公藤内酯环衍生物作为免疫调节剂和抗癌剂
- Patent Title: Triptolide lactone ring derivatives as immunomodulators and anticancer agents
- Patent Title (中): 雷公藤内酯环衍生物作为免疫调节剂和抗癌剂
-
Application No.: US10591358Application Date: 2005-03-02
-
Publication No.: US07863464B2Publication Date: 2011-01-04
- Inventor: Hongwei Yuan , John H. Musser , Dongcheng Dai
- Applicant: Hongwei Yuan , John H. Musser , Dongcheng Dai
- Applicant Address: US CA Redwood City
- Assignee: Pharmagenesis, Inc.
- Current Assignee: Pharmagenesis, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: King & Spalding LLP
- Agent Susan J. Myers Fitch; Peter J. Dehlinger
- International Application: PCT/US2005/006952 WO 20050302
- International Announcement: WO2005/084365 WO 20050915
- Main IPC: C07D307/77
- IPC: C07D307/77 ; A01N43/08
Abstract:
Disclosed are compounds based on lactone ring modifications of triptolide and hydroxylated triptolide, for use in therapy, such as antiproliferative, anticancer, and immunosuppressive therapy.
Public/Granted literature
- US20080287530A1 Tripolide Lactone Ring Derivatives as Immunomodulators and Anticancer Agents Public/Granted day:2008-11-20
Information query
