The technology in this application spreads a signal over an available discontinuous spectrum, such as a radio frequency band, so that the spread signal only occupies the non-contiguous spectrum. In this way, CDMA transmission and reception can be used in a fragmented or non-contiguous spectrum that otherwise would not be useable for direct sequence spreading. Spreading over non-contiguous portions of spectrum is preferably performed without producing unacceptable interference in portions of unavailable spectrum located between the allowed spectrum. By avoiding unacceptable interference in portions of unavailable spectrum located between the allowed spectrum, the unavailable spectrum may be used by other users or services.