Invention Grant
US07867488B2 Use of dendritic cells (DCs) expressing interleukin 12 (IL-12)
有权
使用表达白介素12（IL-12）的树突状细胞（DCs）
- Patent Title: Use of dendritic cells (DCs) expressing interleukin 12 (IL-12)
- Patent Title (中): 使用表达白介素12（IL-12）的树突状细胞（DCs）
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Application No.: US10527679Application Date: 2003-08-29
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Publication No.: US07867488B2Publication Date: 2011-01-11
- Inventor: Thomas Felzmann
- Applicant: Thomas Felzmann
- Applicant Address: AT Vienna
- Assignee: Forschungsinstitut fur Krebskranke Kinder
- Current Assignee: Forschungsinstitut fur Krebskranke Kinder
- Current Assignee Address: AT Vienna
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: ATA1375/2002 20020913
- International Application: PCT/EP03/09591 WO 20030829
- International Announcement: WO2004/024900 WO 20040325
- Main IPC: C12N15/85
- IPC: C12N15/85 ; C12N5/00 ; A61K38/19
Abstract:
The present invention discloses the use of active dendritic cells (DCs) releasing interleukin 12 (IL-12) which are loaded with an antigen against a specific pathogen or a specific tumor and, due to the treatment with lipopolysaccharide (LPS) and interferon-gamma (IFN-γ), release IL-12, for the preparation of a medicament for treating a patient having an infection with said specific pathogen or for treating a patient having said specific tumor.
Public/Granted literature
- US20060177420A1 Use of dendritic cells (dcs) expressing interleukin 12 (il-12) Public/Granted day:2006-08-10
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