Invention Grant
- Patent Title: Treatment of liver cirrhosis and its complications
- Patent Title (中): 治疗肝硬化及其并发症
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Application No.: US11922702Application Date: 2006-06-30
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Publication No.: US07867490B2Publication Date: 2011-01-11
- Inventor: Peter Carmeliet , Isabelle Colle , Anja Geerts
- Applicant: Peter Carmeliet , Isabelle Colle , Anja Geerts
- Applicant Address: BE Zwijnaarde BE Leuven BE Ghent
- Assignee: VIB VZW,Life Sciences Research Partners VZW,Universiteit Gent
- Current Assignee: VIB VZW,Life Sciences Research Partners VZW,Universiteit Gent
- Current Assignee Address: BE Zwijnaarde BE Leuven BE Ghent
- Agency: Foley & Lardner LLP
- Priority: EP05105923 20050630
- International Application: PCT/EP2006/063762 WO 20060630
- International Announcement: WO2007/003609 WO 20070111
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention relates to the field of liver diseases, more particularly to the field of portal hypertension and liver cirrhosis. The invention relates to the use of molecules which can inhibit the binding of placental growth factor (PIGF) to its receptor (VEGFR-1), such as monoclonal antibodies, for the manufacture of a medicament to treat liver cirrhosis, portal hypertension and its complications.
Public/Granted literature
- US20090111974A1 Treatment of Liver Cirrhosis and Its Complications Public/Granted day:2009-04-30
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