Invention Grant
- Patent Title: Isolated polypeptide binding to a sugar chain, polynucleotide encoding the polypeptide and use of the polypeptide and polynucleotide
- Patent Title (中): 与糖链结合的分离的多肽，编码多肽的多核苷酸和多肽和多核苷酸的用途
-
Application No.: US11885282Application Date: 2006-02-27
-
Publication No.: US07867732B2Publication Date: 2011-01-11
- Inventor: Kanji Hori , Haruo Matsuda
- Applicant: Kanji Hori , Haruo Matsuda
- Applicant Address: JP Hiroshima
- Assignee: National University of Corporation Hiroshima University
- Current Assignee: National University of Corporation Hiroshima University
- Current Assignee Address: JP Hiroshima
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: JP2005-056717 20050301
- International Application: PCT/JP2006/303604 WO 20060227
- International Announcement: WO2006/093088 WO 20060908
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C12N1/20 ; C07K14/00 ; C07H21/02
Abstract:
In one embodiment of the present application, a polypeptide capable of binding to a sugar chain is disclosed, particularly a high-mannose-type sugar chain bound to an antibody, more preferably a sugar chain bound to a chicken antibody. Also disclosed is a method for the purification of an antibody (specifically a chicken antibody) as a representative application of the polypeptide. Further disclosed is means for the purification. The polypeptide, BML-17, is a novel lectin made of 168 amino acid residues isolated from Bryopsis maxima. By using BML-17, it becomes possible to purify an antibody (e.g., a chicken antibody) readily and with high efficiency.
Public/Granted literature
- US20090035818A1 Novel Polypeptide, Polynucleotide Encoding the Polypeptide and Use the Polypeptide and Polynucleotide Public/Granted day:2009-02-05
Information query
