Invention Grant
US07868008B2 Substituted isoindolones and their use as metabotropic glutamate receptor potentiators
失效
取代的异吲哚酮及其作为代谢型谷氨酸受体增强剂的用途
- Patent Title: Substituted isoindolones and their use as metabotropic glutamate receptor potentiators
- Patent Title (中): 取代的异吲哚酮及其作为代谢型谷氨酸受体增强剂的用途
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Application No.: US12063018Application Date: 2006-02-15
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Publication No.: US07868008B2Publication Date: 2011-01-11
- Inventor: Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
- Applicant: Bradford Van Wagenen , Radhakrishnan Ukkiramapandian , Joshua Clayton , Ian Egle , James Empfield , Methvin Isaac , Fupeng Ma , Abdelmalik Slassi , Gary Steelman , Rebecca Urbanek , Sally Walsh
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agent Kenneth F. Mitchell
- International Application: PCT/US2006/005247 WO 20060215
- International Announcement: WO2007/021309 WO 20070222
- Main IPC: C07D209/46
- IPC: C07D209/46 ; C07D401/06 ; C07D401/14 ; A61K31/4035 ; A61K31/454
Abstract:
The present invention is directed to compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
Public/Granted literature
- US20090111830A1 SUBSTITUTED ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS Public/Granted day:2009-04-30
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