Invention Grant
- Patent Title: Search for cancer markers by a screening method
- Patent Title (中): 通过筛选方法搜索癌症标志物
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Application No.: US11987983Application Date: 2007-12-06
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Publication No.: US07868136B2Publication Date: 2011-01-11
- Inventor: Kazuki Sasaki , Kae Sato , Ken Yamaguchi
- Applicant: Kazuki Sasaki , Kae Sato , Ken Yamaguchi
- Applicant Address: JP Tokyo JP Saitama
- Assignee: Japan as represented by President of National Cancer Center,Advanced Life Science Institute, Inc.
- Current Assignee: Japan as represented by President of National Cancer Center,Advanced Life Science Institute, Inc.
- Current Assignee Address: JP Tokyo JP Saitama
- Agency: Foley & Lardner LLP
- Priority: JP2001-292348 20010925; JP2002-141959 20020516
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention relates to a method of concentrating low molecular weight peptides in the supernatant of serum-free cultured cells, said method comprising allowing the peptides to bind to a strong cation exchanger under an acid condition, and eluting them under an alkali condition to concentrate the peptide.Furthermore, peptides having the amino acid sequence as set forth in SEQ ID NO: 1 or 2, and a method of screening cancer markers using antibody to these peptides, are disclosed.
Public/Granted literature
- US20080188008A1 Search for cancer markers by a novel screening method Public/Granted day:2008-08-07
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