Invention Grant
- Patent Title: 5-heteroaryl thiazoles and their use as PI3K inhibitors
- Patent Title (中): 5-杂芳基噻唑及其作为PI3K抑制剂的用途
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Application No.: US11667064Application Date: 2005-11-07
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Publication No.: US07868188B2Publication Date: 2011-01-11
- Inventor: Malena Bengtsson , Joakim Larsson , Grigorios Nikitidis , Peter Storm , John Peter Bailey , Edward Jolyon Griffen , Jean-Claude Arnould , Thomas Geoffrey Colerick Bird
- Applicant: Malena Bengtsson , Joakim Larsson , Grigorios Nikitidis , Peter Storm , John Peter Bailey , Edward Jolyon Griffen , Jean-Claude Arnould , Thomas Geoffrey Colerick Bird
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Priority: SE0402735 20041109
- International Application: PCT/GB2005/004268 WO 20051107
- International Announcement: WO2006/051270 WO 20060518
- Main IPC: C07D207/00
- IPC: C07D207/00
Abstract:
The invention provides thiazole derivatives of formula (I), or pharmaceutically acceptable salts thereof in which Ring A, R1, R2 and R3 are as defined in the specification; a processes for their preparation; pharmaceutical compositions containing them; and their use in therapy, for example in the treatment of disease mediated by a PI3K enzyme and/or a mTOR kinase.
Public/Granted literature
- US20080132502A1 5-Heteroaryl Thiazoles And Their Use As PI3K Inhibitors Public/Granted day:2008-06-05
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