A medication managing apparatus includes a medicine package case and a main body unit removably storing the medicine package case. The medicine package case includes blocks each storing a medicine package, openings provided at walls of each block and formed at positions facing each other such that the medicine package stored in the block is sandwiched therebetween, and an openable/closable cover. The main body unit includes a sensor portion (a medicine package sensor) disposed corresponding to each opening at the opposing walls of each block, to sense a medicine package based on that the medicine package stored in the block blocks a gap between a pair of openings, and a switch lever and a micro-switch (a medicine package case sensor) sensing attachment/removal of the medicine package case to/from the main body unit.